Protein binding events are key to understanding a specific protein’s function in the cell. A study of these interactions in healthy or diseased cells can help to determine the role of a particular protein in a disease process.
Mid-IR spectra are characterized by their high information content with such specificity, that substances can be identified on the basis of their IR spectrum in the same way as a finger print.
Membrane-associated proteins are of great significance in intra- and intercellular signal transmission. To be able to obtain the conformation and hence their functionality, it is necessary to examine these proteins in their native membrane environment.
Bio-FTIR by micro-biolytics expands proteomics studies by another dimension, because it provides detailed functional data on protein interactions and conformational changes. With its user-friendly automation micro-biolytics brings the option of Bio-FTIR directly to the user.