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With the unique AquaSpec™ Technology, micro-biolytics offers a new class of analytical technology within liquid solutions. This cutting edge technology is based on middle infrared spectroscopy which is recognized as the most sensitive optical absorption technique for detecting all molecular details in lowly concentrated organic compounds (e.g. compared to NIR or UV/VIS). The AquaSpec™ Technology platform provides fast and powerful tools to detect the state as well as changes of an observed solution. By means of the fully automated MIRA – Analyzer Series, AquaSpec™ Technology offers a wide range of applications in pharmaceutical, process analytical, clinical and other analytical fields:


Pharmaceutics – examine stability and formulations studies

The stability of products is an important aspect for the pharmaceutical industry. By AquaSpec™ Technology, aqueous as well as organic solutions can be investigated in the range of minutes without sample pre-treatment, yielding detailed information about the current state of the measured sample. In many applications AquaSpec™ Technology is therefore a better choice to HPLC and GC.


Proteomics - identify and characterize proteins

Protein identification, interaction and characterization are the focal points of proteomics interest especially for the pharmaceutical industry. AquaSpec™ Technology generates detailed information about data of molecular interactions and conformational changes of proteins in their native environment, without the need to immobilize or even include a marker to the proteins.


PAT and Manufacturing QC - control quality standards and optimize processes

In PAT, the main challenge is to find out properties and compositions of relevant substances with highest quality demands. micro-biolytics develops individual AquaSpec™ PAT solutions and provides overall customer support. AquaSpec™ MIRA Analyzers can be implemented for both, laboratory and process environment (atline/online) and are in line with the FDA PAT initiative.


Diagnostics - determine diseases by specific patterns

Reliable and fast diagnostics increasingly gain importance for public health. Diagnostic solutions based on AquaSpec™ Technology benefit from the fact that some diseases generate specific changes in the metabolic pattern of blood or other body fluids. These characteristic spectroscopic markers can be used by AquaSpec™ MIRA Analyzers for identification and classification in seconds to minutes.

Press release
Prof.Dr.D.Wolf
The head of the scientific advisory board of micro-biolytics, Prof. Dr. D. Wolf, is given the ‚Landesforschungspreis 2007’. Prof. Dr. Frankenberg, Minister of Science of Baden-Württemberg presented this tribute to Prof. Wolf to honour „outstanding research results and excellent researchers“.
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EC Evaluation
In 2006, micro-biolytics was evaluated by the European Commission (IRMM/EC) in BSE diagnostics: the ante mortem BSE test based on the AquaSpec™ Technology.
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Room for Growth
For the expansion of laboratory-, production- as well as service-space, mbio has moved to a new location at Esslingen (Stuttgart). The expansion was necessary to cope with increasing service and production demands regarding the AquaSpecTM Technology.
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